Research for chemotherapy-free treatment at Hope Clinical Trials Facility is a success!


A study which has involved researchers from Hope Against Cancer’s Clinical Trials Facility in Leicester has shown promising results for patients with Chronic Lymphocytic Leukaemia (CLL). The study, which was led by Hope funded researcher, Professor Martin Dyer, could see a future where patients can receive chemotherapy-free treatment.

CLL is the most common form of adult chronic leukaemia, where chemotherapy is typically the first treatment for it, however this isn’t always a suitable solution for older patients with other health issues. The researchers combined a protein called BCL2, which effectively kills the CLL cells, with a drug called Obinutuzumab. This was clearly effective as it was found that 95% of those treated at the Hope Clinical Trials Facility had a complete remission rate, which means there were no signs of leukaemia in the blood or in the scans with the patients not having any symptoms. 

The results have been exceptional and the patients who took part in the clinical trial haven’t had to go through the awful side effects of chemotherapy. Professor Martin Dyer is a professor of haemato-oncology and is the director of the Ernest and Helen Scott Haematology Research Institute at the University of Leicester. He has said: “This new treatment is producing extraordinary results” 

He added: “The high response rates and remissions have made us optimistic that this treatment could become a standard of care for CLL in the future, I am delighted that we were able to offer patients in Leicester the opportunity to take part in this trial at the Hope Clinical Trials Facility”. 

Hope Against Cancer is a Leicestershire and Rutland based charity who fund cutting edge research and have made clinical trials available to local people. Nigel Rose, the Chief Executive at Hope has said: “We are thrilled to see such incredible results from the Hope Clinical Trials Facility, this simply could not happen without the fantastic support from the people of Leicestershire and Rutland who fundraise, donate, take part in and attend Hope’s events.”

 If you want to find out more information about the Hope Against Cancer Clinical Trials Facility, or how you can help them raise money to fund vital research projects like this, then you can visit their website: